[PDF.99ss] Strategies to Circumvent the CFTR Defect in Cystic Fibrosis

Strategies to Circumvent the CFTR Defect in Cystic Fibrosis

[PDF.sr69] Strategies to Circumvent the CFTR Defect in Cystic Fibrosis

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 |  2015-02-09 | Original language:English | PDF # 1 |  10.00 x.66 x8.00l,1.23 | File type: PDF | 278 pages

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Mutations within the gene encoding for the chloride ion channel CFTR results in cystic fibrosis, the most common autosomal recessive genetic disease in the Caucasian population. CFTR regulates absorption and secretion mechanisms across intestinal and airway mucosae. Although the intestinal phenotype can be clinically handled, chronic infection and inflammation of the lungs of CF patients remains the principal cause of morbidity and mortality. The aim of this collection o...

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